{"id":3791,"date":"2018-09-04T13:06:03","date_gmt":"2018-09-04T07:36:03","guid":{"rendered":"https:\/\/www.oyspa.com\/blog\/?p=3791"},"modified":"2018-09-04T13:06:03","modified_gmt":"2018-09-04T07:36:03","slug":"how-the-brain-cells-talk","status":"publish","type":"post","link":"https:\/\/www.oyspa.com\/blog\/news\/how-the-brain-cells-talk\/","title":{"rendered":"How the brain cells ‘talk’"},"content":{"rendered":"

In a new technique, scientists have developed a way to see\u00a0brain cells\u00a0talk\u00a0– to actually see neurons communicate in bright, vivid colour.
\nThe new lab technique is set to provide long-needed answers about the brain and\u00a0neurological diseases\u00a0such as Alzheimer’s disease, schizophrenia and depression. Those answers will facilitate new and vastly improved treatments for conditions that have largely resisted scientists’ efforts to understand them.<\/p>\n

\"\"<\/a>
\nResearcher J. Julius Zhu said, “Before we didn’t have any way to understand how [such neurotransmissions] work. In the case of Alzheimer’s, in particular, we spent billions of dollars and we have almost no effective treatment. … Now, for the first time, we can see what is happening.”
\nTo demonstrate the technique’s effectiveness, Zhu’s team in Charlottesville and colleagues in China have used it to visualize a poorly understood neurotransmitter called acetylcholine. “It affects Alzheimer’s, schizophrenia, emotions, depression, all kind of emotion-related diseases and mental problems,” added Zhu.
\nAcetylcholine also plays critical roles elsewhere in the body, such as regulating insulin secretion in the pancreas and in controlling stress and blood pressure.
\nDrugs designed to combat Alzheimer’s disease actually inhibit acetylcholinesterase, an enzyme that degrades acetylcholine, to boost the effect of diminishing acetylcholine released in the brain.
\n“These drugs are not very effective,” Zhu said. “They only offer a minor improvement, and once you stop the drug [the symptoms] just seem much worse. So probably in trying to treat these patients, you temporarily enhance them but you actually make them even worse.”
\nBy being able to see acetylcholine and other neurotransmitters in action in fluorescent color, doctors will be able to establish a baseline for good health and then work to restore that in patients with\u00a0neurological diseases.
\nThe full findings are present in the journal- Nature Biotechnology.<\/p>\n","protected":false},"excerpt":{"rendered":"

In a new technique, scientists have developed a way to see\u00a0brain cells\u00a0talk\u00a0– to actually see neurons communicate in bright, vivid […]<\/p>\n","protected":false},"author":11,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[4],"tags":[],"class_list":["post-3791","post","type-post","status-publish","format-standard","hentry","category-news"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/paZdga-Z9","jetpack-related-posts":[],"jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/posts\/3791","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/comments?post=3791"}],"version-history":[{"count":1,"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/posts\/3791\/revisions"}],"predecessor-version":[{"id":3794,"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/posts\/3791\/revisions\/3794"}],"wp:attachment":[{"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/media?parent=3791"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/categories?post=3791"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oyspa.com\/blog\/wp-json\/wp\/v2\/tags?post=3791"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}